Daughter of a music professor; trained classically in her home country of Russia, Regina's passion for music was clear from childhood. Once she completed her studies she moved to the Bronx, New York and her life has never been the same. Influenced by her Russian and Jewish roots, as well her new love for the city Regina's songwriting took off. It was in the underground music scene of the East Village where she found fame. Still, her music is always evolving, channeling influences like Chopin, Janis Joplin, to experimenting with unusual instruments and vocal styles, Regina never ceases to surprise.
After a number of self-funded and distributed albums, she finally got her first proper release in 2004 when Warner Brothers re-released her 2003 self-released album Soviet Kitsch. She released the highly anticipated follow-up album, Begin To Hope, in 2006. The single from the album, "Fidelity", was a big hit and helped the album peak at number 20 in the US Billboard chart. Her fifth full album, Titled Far, was a smash hit, it entered the US charts at number three and raised Regina's profile worldwide. In 2010 she performed at President Obama's reception at the White House. Her latest album, titled What We Saw from the Cheap Seats also entered the US album chart at number three.
Regina first toured nationally with The Strokes and this was quickly followed by a tour supporting The Kings of Leon, where she played in front of many famous venues at max capacity, like the Warner Theatre in Washington, D.C. A series of headline theater shows followed the release of the album Far and in recent years she has made frequent appearances during the European Summer Festival season. Away from music, Regina does a great deal of work for human rights charities and has raised money for Doctors Without Borders helping earthquake victims.